Another point to highlight here is that it helps to contrast acute stressors vs. chronic stressors. I'd characterize decades of insulin-raising (or roughage/ind

Another point to highlight here is that it helps to contrast acute stressors vs. chronic stressors. I'd characterize decades of insulin-raising (or roughage/indigestables-heavy) overfeeding as a chronic stressor, and a 3-week fast every month or other month too, whereas intermittent fasting is probably more of an acute stressor --- somewhat akin to "the right amount, not too little not too much" of exercise, the kind of stressor that rapidly mobilizes heightened repair and protection mechanisms, as well as stored excess resources to pay for this. Not a bad deal.