As long as the non-x86 architecture is both 64 bit and little endian, I think this is true. However, in the absence of those two properties not at all. There

As long as the non-x86 architecture is both 64 bit and little endian, I think this is true. However, in the absence of those two properties not at all. There are many mainstream linux code bases which are either inconsistently endian-clean (meaning they are for some operations but not all) or are straight up broken. This becomes really visible debugging bizarre, impossible bugs on BE architectures.