Are there many that actually depend on syncing up to the physical refresh and not just fiddling with registers at the right point in signal/pixel space? The onl

Are there many that actually depend on syncing up to the physical refresh and not just fiddling with registers at the right point in signal/pixel space? The only thing I can think of is some old-school light gun games, which involve a physical sensor pointed at the screen and thus depend on sufficiently high brightness and sufficiently low input lag (and so almost always fail on LCDs).