What is outside the frame of reference? QM isn't outside the frame of reference of the scientific method though. It's as proven mathematically and empirically

What is outside the frame of reference? QM isn't outside the frame of reference of the scientific method though. It's as proven mathematically and empirically as general relativity is. So the only irrational thing here would be to claim that the quantum world isn't as real as the classical physical world. Agree on the last part though. we might (are most likely) all be missing the point