4 ms·

But that's not how caffeine is removed from the brain - that entire flowchart says "liver cell". Is one to understand that as the liver cleans blood of caffeine

But that's not how caffeine is removed from the brain - that entire flowchart says "liver cell". Is one to understand that as the liver cleans blood of caffeine, and this low-caffeine blood eventually goes up to the brain, caffeine diffuses somehow (across the blood/brain barrier) into the bloodstream and is then carried to the liver?

pizza 10y ago
Essentially, to my knowledge.. of relevance: https://en.wikipedia.org/wiki/Distribution_(pharmacology) https://en.wikipedia.org/wiki/Distribution_(pharmacology) https://en.wikipedia.org/wiki/Pharmacokinetics https://en.wikipedia.org/wiki/Pharmacokinetics https://en.wikipedia.org/wiki/ADME https://en.wikipedia.org/wiki/ADME https://en.wikipedia.org/wiki/Compartment_(pharmacokinetics) https://en.wikipedia.org/wiki/Compartment_(pharmacokinetics) https://en.wikipedia.org/wiki/Clearance_(pharmacology) https://en.wikipedia.org/wiki/Clearance_(pharmacology) https://en.wikipedia.org/wiki/Plasma_protein_binding https://en.wikipedia.org/wiki/Plasma_protein_binding