You can use PCI risers to give yourself some more flexibility as to how your cards are plugged in. However, please make sure you have enough PCI x16 or x8 slots

You can use PCI risers to give yourself some more flexibility as to how your cards are plugged in. However, please make sure you have enough PCI x16 or x8 slots. If you're not running a server motherboard, I highly doubt you have enough PCI lanes to fit more than two or three cards.