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How would we check these results in humans? Can we safely biopsy someone's heart?
by StClaire 10y ago
How would we check these results in humans? Can we safely biopsy someone's heart?
- untilHellbanned 10y agono. more practical to use proxies (this is the hard part) from more readily available tissues like the blood.
- forgotpwagain 10y agobiopsies of the heart can be done, but only for compelling reasons. it carries non-trivial risk to the individual. untilHellbanned described the better way -- ideally, there would be some sort of biomarker in the blood that serves as a proxy for the level in the heart. But how do you find it and validate it? It's challenging (at best...)
- gozur88 10y agoI would think for research purposes autopsies would give you better data than biopsies, and without any risk.