They're not mutually exclusive terms. You can have one without the other. The database that supports zero knowledge queries can be a plaintext patent database.

They're not mutually exclusive terms. You can have one without the other. The database that supports zero knowledge queries can be a plaintext patent database. You can do research without leaking what you're researching, however the records themselves are not confidential between a sender and recipient therefore it would be wrong to claim such a system is E2E, even though it is zero knowledge. Take your example, you upload 10 notes to a server with device #1 and then retrieve a few of them with device #2. The server knows exactly what 10 notes you uploaded and exactly which of 3 of the 10 were read by the second device. It also knows when the uploads and downloads occur. Since it knows #2 downloaded a subset of what #1 uploaded, it can conclude that #1 and #2 have some kind of relationship. (eg. Both are your devices, or one device belongs to your friend with whom you have shared 3 of your notes) This is E2E but not zero knowledge. Now imaging incorporating both E2E and zero knowledge techniques into a note sync system: 1) All notes are encrypted end to end. That is, the servers that store and route notes never learn the secrets necessary to decrypt them 2) Notes sent into the system are routed through a mixnet that uses verifiable shuffles so no one passively watching all of the users and system (or actively running malicious servers or clients) can learn who is sending which note ciphertext. 3) Note ciphertexts are retrieved from the system using private information retrieval so that observers and cheating servers don't learn who is receiving which one or when it's been received. This system isn't going to learn anything about how many devices you have or who you share with. And it's going to prevent further analysis of metadata: For example, device #1 and #2 keep matching sets of notes and they frequently connect from the same IP addresses, therefore it's safe to assume these devices are owned by the same person. Device #3 requests a subset of notes that were uploaded by #1 and #2, but always from a different country. Now #3 retrieves a note posted by #2 from the same IP address that #1 used recently. Therefore it's safe to assume that the owner of #3 is visiting the owner of #1 and #2.