There's not really a lot of detail in your question so I've no idea what sort of solution(s) you're interested in. One suggestion, however - if it's a linux/un

There's not really a lot of detail in your question so I've no idea what sort of solution(s) you're interested in. One suggestion, however - if it's a linux/unix based box you're backing up, you're looking for a hosted solution and you care about security, tarsnap is excellent.