Sorry, I blended together several issues: * My wrists used to hurt a lot from bizarre keybindings that use the control key (I used to use emacs a lot), than fr

Sorry, I blended together several issues: * My wrists used to hurt a lot from bizarre keybindings that use the control key (I used to use emacs a lot), than from mouse usage. Remapping to the caps is no use (strains my left little finger and left upper side of the hand). Remapping to alt (or to the apple key, in a powerbook) helped a lot, but still too many control pushes. * The mouse slows me down, way more than hurts my wrists. * I use Blender a lot. Using the mouse for Blender is no problem regarding my wrists. The trick for me is: extend the arm to fully rest in the table, flat, so that the mouse ends up nearly behind the laptop.