4 ms·
Supposedly, the number of adenosine receptors in your brain increases over time with caffeine consumption, creating a tolerance to caffeine. I've read articles
by ValentineC 10y ago
Supposedly, the number of adenosine receptors in your brain increases over time with caffeine consumption, creating a tolerance to caffeine.
I've read articles [1] which suggest that cycling off caffeine for 7-12 days helps reset the number of adenosine receptors to the baseline.
[1] http://www.smithsonianmag.com/science-nature/this-is-how-your-brain-becomes-addicted-to-caffeine-26861037/ http://www.smithsonianmag.com/science-nature/this-is-how-you...
- xenihn 10y agoI've always thought that changes to receptors are how tolerance to any stimulant works.
- coldcode 10y agoThere is a limit to how many receptors you can have, which limits how much "wakeup" coffee can produce. Once you hit the limit and fill them up, the only affect you get from more coffee are the negative problems. I vaguely remember it being like 400mg of caffeine or something like that.