For U2F at least, Bluetooth solutions should be arriving. If Yubico does its on (they have said that they are working on it) they might additionally let you use

For U2F at least, Bluetooth solutions should be arriving. If Yubico does its on (they have said that they are working on it) they might additionally let you use the OTP stuff. That said, LassPass says that when Firefox supports U2F, they will also try to support it. So maybe the OTP stuff is not that important. Dashlane Password Manager already supports it.