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It's possible Fatal Famililal Insomnia kills you by some other mechanism, and the sleeplessness is just a symptom, I figure. I don't think we know that the slee
by roywiggins 10y ago
It's possible Fatal Famililal Insomnia kills you by some other mechanism, and the sleeplessness is just a symptom, I figure. I don't think we know that the sleeplessness is the thing that kills you.
"Like all prion diseases, FFI is a progressive neurodegenerative disease, which means over time there are fewer neurons (nerve cells). Loss of neurons in the thalamus, as well as other mechanisms not yet fully understood, cause the symptoms of FFI."
"Although the main target of FFI is the thalamus, other parts of the brain are affected as well including the inferior olives. The inferior olives are part of the medulla oblongata and are important for coordinating our movements (motor control). Losing neurons in the inferior olives can make it harder for a person to control their movements as seen in later stages of FFI."
https://rarediseases.info.nih.gov/diseases/6429/fatal-familial-insomnia https://rarediseases.info.nih.gov/diseases/6429/fatal-famili...
When your whole brain is going haywire due to neuron loss, attributing death to sleeplessness seems premature.
- majkinetor 10y ago> When your whole brain is going haywire due to neuron loss, attributing death to sleeplessness seems premature. Or it could be another way around, as its not easy to have experiments like this I guess we can never know. But yes, that is certainly possible that in FFI you die due to some other reason. I didn't see that info you provided but I remember reading in NGeo many years back that FFI people seem healthy in other aspects. There was 1 experiment with mices tho - after 32 days they all died witout sleep: [1] http://health.howstuffworks.com/mental-health/sleep/basics/die-if-never-sleep.htm http://health.howstuffworks.com/mental-health/sleep/basics/d...