The "Asian flush" response is the result of a mutation that is believed to have arisen in Asia, and is relatively uncommon in Europe and Africa. So the ancestr

The "Asian flush" response is the result of a mutation that is believed to have arisen in Asia, and is relatively uncommon in Europe and Africa. So the ancestral (savannah) state may have been tipsy indeed. The derived allele appears to have been positively selected in Asia, possibly because it is protective against alcohol dependency, but the selective pressure hasn't been conclusively established.