Kratom user here... it's definitely promising, and for the same reason as the other drug in the article: more G Protein activation, less β-arrestin activation.

Kratom user here... it's definitely promising, and for the same reason as the other drug in the article: more G Protein activation, less β-arrestin activation. Here's a study (free access) from Columbia University researchers on the activation patterns of Kratom alkaloids: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5189718/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5189718/