4 ms·
How LSD binds to the brain, and why trips last so long
- cypherpunks01 10y agoSource study published in Cell, "Crystal Structure of an LSD-Bound Human Serotonin Receptor" HTML http://www.cell.com/cell/fulltext/S0092-8674(16)31749-4 http://www.cell.com/cell/fulltext/S0092-8674(16)31749-4 PDF http://www.cell.com/cell/pdf/S0092-8674(16)31749-4.pdf http://www.cell.com/cell/pdf/S0092-8674(16)31749-4.pdf
- meowface 10y agoThis is really interesting, but only solves one of the many puzzles of LSD. I hope we'll someday learn how LSD's presence in these receptors can sometimes alter consciousness so profoundly.
- lawpoop 10y agoIsn't this just really the general puzzle of how neurotransmitters work in the first place? We know their effects, in the broadest strokes (e.g. dopamine == reward), but we don't know precisely how they create those effects.