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Happy babies! As a point of interest, this type of engineered T-cell treatment has its roots in research at the Weizmann Institute in Tel Aviv. They demonstra
by blisterpeanuts 10y ago
Happy babies! As a point of interest, this type of engineered T-cell treatment has its roots in research at the Weizmann Institute in Tel Aviv. They demonstrated the use of CARs modified T-cells in curing leukemic disease in rats and mice several years ago.
Their research was expanded to human trials at Univ. of Penn. where 27 of 29 patients with incurable leukemia and most of whom had a prognosis of death within a few months went into remission and showed no sign of the disease.
This modality may work with other forms of cancer; engineered T-cells that can enter every capillary in the body could potentially wipe out entire colonies of cancer cells. The potential is enormous, as are the challenges; cancers can be very difficult to differentiate from healthy tissue.
[1]http://www.timesofisrael.com/breakthrough-cancer-cure-has-deep-israeli-roots/ http://www.timesofisrael.com/breakthrough-cancer-cure-has-de...
- eliben 10y agoThanks for the extra info - very interesting. I'm always curious about whether these trials were followed later on as well. I mean those 27 of 29 patients, what is their state now? Still healthy? And how long ago did this trial occur?