3 ms·
I am a scientist and I am impartial if that is good enough :) The major problem is the same as it has been for the last 30 years - delivery. You can make the m
by danieltillett 10y ago
I am a scientist and I am impartial if that is good enough :)
The major problem is the same as it has been for the last 30 years - delivery. You can make the most amazing molecular machinery for modifying genes, but if you can't get it into a very high percentage of adult cells then it is useless for most treatment purposes. We still don't have any good delivery systems that work on all cell types and doesn't come with the very real risk of death via immune hyper reaction.
- moh_maya 10y agoThis. Completely. Also, I still worry about off-target edits / changes, though that is less of a concern with the technologies available today compared to even 5 years back. But delivery remains the biggest challenge.
- lisivka 10y agoIMHO, in some cases, cells can be converted into stem cells, repaired in lab conditions, and then delivered back into damaged organ or area.
- danieltillett 10y agoYes some haematological diseases can be treated this way, but not much else. We really need much better delivery systems that work in all tissue types.