Alexander Fleming gave the following warning, way back in his 1945 Nobel speech: It is not difficult to make microbes resistant to penicillin in the labora

Alexander Fleming gave the following warning, way back in his 1945 Nobel speech: It is not difficult to make microbes resistant to penicillin in the laboratory by exposing them to concentrations not sufficient to kill them, and the same thing has occasionally happened in the body. From page 93 in https://www.nobelprize.org/nobel_prizes/medicine/laureates/1945/fleming-lecture.pdf https://www.nobelprize.org/nobel_prizes/medicine/laureates/1... BBC did a very good radio segment about the penicillin discovery in their "50 Things That Made the Modern Economy" radio series: http://www.bbc.co.uk/programmes/p04pfn2z http://www.bbc.co.uk/programmes/p04pfn2z