https://en.wikipedia.org/wiki/Human_Genome_Project https://en.wikipedia.org/wiki/Human_Genome_Project "The genome published by the HGP does not represent the s

https://en.wikipedia.org/wiki/Human_Genome_Project https://en.wikipedia.org/wiki/Human_Genome_Project "The genome published by the HGP does not represent the sequence of every individual's genome. It is the combined mosaic of a small number of anonymous donors, all of European origin." I work at a for-profit DNA company which sequences humans for genealogical purposes. The human reference, as we call it, has been through several 'revisions'. My company uses anywhere from "build 36" to "build 38", depending on the specific sequencing product purchased. It's an ongoing effort to upgrade older products to use the newer sequencing version: each revision may change, add, or remove genomic locations of specific named variants. That can wreak havoc, of course, when trying to translate older data to the newer revision. Customers would of course notice right away if their genome data were to change on them! It creates rather a conundrum to solve.