He's not 'hacking his own genes' though, is he? There's no modification of his germ cells, nor is there stable incorporation of the exogenous material into the

He's not 'hacking his own genes' though, is he? There's no modification of his germ cells, nor is there stable incorporation of the exogenous material into the genome of the affected cells - more just transient expression of the protein he's interested in. Giving the extraordinary complexity of the ageing process, with the interplay between multiple genes, each with multiple splice variants and post-translation modifications, and whose expression is modulated by both genetic and epigenetic factors, the chance of success with this approach is minimal.