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The reason r/fitness says this is because for active people it largely holds true, with the exception of certain bulking/cutting phases for lifters. It's people

The reason r/fitness says this is because for active people it largely holds true, with the exception of certain bulking/cutting phases for lifters. It's people who are sedentary, or in chronic caloric surplus where the macros become more of a concern. You're not going to wreak havoc on your insulin sensitivity by having a Coke every day if you get up and run a 10k every morning, because things like glycogen levels will be replenished. But if you're sedentary, your body deals with it very differently.

xherberta 10y ago
The composition of one's microbiome is also a major factor in metabolism (and is interrelated with activity level, too.) https://microbewiki.kenyon.edu/index.php/Firmicutes_and_Obesity https://microbewiki.kenyon.edu/index.php/Firmicutes_and_Obes... The article didn't tread much into the satiety effect: while sugar- and carb-laden foods generally leave you wanting more, it's difficult to overeat naturally fatty things like bacon, cream, or eggs. Until just now, these foods have been frowned upon so hard that few people think of combining them with veggies to create tasty, affordable, satisfying, and nutritious meals.
- kmm 10y ago
  The linked page doesn't say the microbiome influences metabolism, only that it is suspected to be involved in digestion and fat absorption. Metabolism doesn't happen in the gut, but in the cells and mostly in the mitochondria. It is controlled by the hypothalamus, which keeps your body at the same temperature, as this is the bulk of what food energy is used for.
- kapauldo 10y ago
  This does not explain the 600% obesity increase.
jrowley 10y ago
Yes this is it exactly. It's not so clean cut to say a 'calorie isn't a calorie' because for me an active recreational distance runner, I can pretty much eat/drink my calories however I please while remaining relatively thin.
Y201K 10y ago
Definitely. However, it's also just the most important factor in weight control, with macronutrients, nutrient timing, and food composition playing lesser roles.

xherberta 10y ago

The composition of one's microbiome is also a major factor in metabolism (and is interrelated with activity level, too.) https://microbewiki.kenyon.edu/index.php/Firmicutes_and_Obesity https://microbewiki.kenyon.edu/index.php/Firmicutes_and_Obes... The article didn't tread much into the satiety effect: while sugar- and carb-laden foods generally leave you wanting more, it's difficult to overeat naturally fatty things like bacon, cream, or eggs. Until just now, these foods have been frowned upon so hard that few people think of combining them with veggies to create tasty, affordable, satisfying, and nutritious meals.

kmm 10y ago
The linked page doesn't say the microbiome influences metabolism, only that it is suspected to be involved in digestion and fat absorption. Metabolism doesn't happen in the gut, but in the cells and mostly in the mitochondria. It is controlled by the hypothalamus, which keeps your body at the same temperature, as this is the bulk of what food energy is used for.
kapauldo 10y ago
This does not explain the 600% obesity increase.

jrowley 10y ago

Yes this is it exactly. It's not so clean cut to say a 'calorie isn't a calorie' because for me an active recreational distance runner, I can pretty much eat/drink my calories however I please while remaining relatively thin.

Y201K 10y ago

Definitely. However, it's also just the most important factor in weight control, with macronutrients, nutrient timing, and food composition playing lesser roles.