3 ms·
Taking acetaminophen after drinking is extremely dangerous. It's potentially the leading cause of liver damage in the United States. The thing is that the dama
by Declanomous 10y ago
Taking acetaminophen after drinking is extremely dangerous. It's potentially the leading cause of liver damage in the United States.
The thing is that the damage only occurs in a specific instance, that is somewhat rare even if taken with alcohol. It occurs when the typical biochemical pathway for processing tylenol is saturated, which typically doesn't happen, but when it does it causes a lot of damage very quickly.
A lot of drugs are extremely dangerous when not taken as prescribed, but the danger exists only in edge cases. So you could have 99 people saying "this drug is fine" and the drug will kill that 100th person every single time because of a particular mutation in a biochemical pathway.
The Yelp method is a stupid way to regulate drugs because making correct risk assessments isn't something non-professionals can do. It's not like Amazon, where a buying a charger that mysteriously doesn't work with your phone is an inconvenience -- people are risking their health and their life.
The site would be a bad idea even the power to review was limited to MDs. MDs are not all equally qualified to review drugs. Even if they know a lot about their specialty, they don't understand everything they need to know to prescribe drugs safely. This is why we have pharmacists. Their job is to basically understand all of the ways drugs work to predict novel interactions. Dumping a bunch of mystery drugs on the market is going to destroy that safety net. Furthermore, it's insane to think you can properly measure the efficacy of a drug by having doctors write reviews about it. Double-blind studies are a necessity for a reason.
- baddox 10y agoI don't disagree with your broader point that "Yelp for drugs" is insufficient, but I'd still like to see some sources for your specific claims about Tylenol. From what I can tell from quick Googling, liver damage is quite rare unless the dosages are well beyond the recommendation, or taken habitually, or combined with an already extreme and dangerous dose of alcohol.