3 ms·
This. There are very very few ways to deal with fungal infections, the most common pathway is one that is targeted by the azoles agents. Yet analogs of azoles a
by devoply 10y ago
This. There are very very few ways to deal with fungal infections, the most common pathway is one that is targeted by the azoles agents. Yet analogs of azoles are routinely used not to kill fungus infections but to merely control them on plants. They are used wholesale for this purpose. So guess what, there is huge resistance popping up in fungal infections that infect human beings against azole agents. Add this problem to global warming and you have a huge looming problem not just with bacteria, but fungus and molds as well. And all the new drugs in the past two decades have targeted the same pathway. So we're sort of lost on how to deal with fungus going forward.