The prevalent and hostile view exists because this is a pretty dubious study design, and there's a ridiculous degree of financial entanglement in many of these

The prevalent and hostile view exists because this is a pretty dubious study design, and there's a ridiculous degree of financial entanglement in many of these "trials". Lots of bad data doesn't necessarily help anyone. If the problem really is "This area doesn't have enough money", then the same money being used to buy into the trial could have funded a proper double-blind trial. And this is from the perspective of someone who does support the use of non-randomized evidence in medicine.