I wonder if you could run a paid study with a proper control group. Perhaps have everyone pay to participate, administer the treatment to half of them, and at t

I wonder if you could run a paid study with a proper control group. Perhaps have everyone pay to participate, administer the treatment to half of them, and at the end of the study refund some amount of money (all? all + interest?) to the ones who received a placebo. That way they've only donated their time.