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Not exactly, Neanderthal admixture of 1-4% of the genome is present in all populations except sub-Saharan Africans. https://en.wikipedia.org/wiki/Archaic_human
by jboggan 10y ago
Not exactly, Neanderthal admixture of 1-4% of the genome is present in all populations except sub-Saharan Africans.
https://en.wikipedia.org/wiki/Archaic_human_admixture_with_modern_humans https://en.wikipedia.org/wiki/Archaic_human_admixture_with_m...
- rootbear 10y agoWhat I found interesting is that, while any given modern human has no more than about 4% Neanderthal DNA, it isn't the same 4% in everyone. About 20% of the Neanderthal genome is found in humans. I'm not sure what this says about interbreeding. And then there's the Denisovans... I gotta get my DNA done...
- juskrey 10y agoI think this says a lot about spurious correlations in DNA "science".
- Symmetry 10y agoIt says that 80% of the Neanderthal genome produces a selective disadvantage?
- miguelrochefort 10y agoI got my DNA done. 3.3% Neanderthal. That's 99th percentile. Not sure if that means anything.
- Camillo 10y agoIf 1-4% of the Eurasian genome comes from Neanderthals, but sub-Saharan Africans have no Neanderthal genes, does that mean that the EA genome differs from the SSA one by 1-4%? And even more so the Melanesian genome, which has 4-6% Denisovan DNA. But at the same time, chimpanzees and humans supposedly share over 99% of their genome. How is that possible? Are these all percentages of the same whole, or is there something else going on?
- adrianN 10y agoIt's important which bits are different too. The absolute percentage doesn't tell you the whole story.
- scatters 10y agoThat's measuring different things. We can tell whether a particular copy of a gene came from the Neanderthal gene pool or the main SSA gene pool by looking at its sequence (esp. at SNPs), but the overall base pair sequence of that gene will still be 99.9% the same. When we say that chimpanzees and humans share 99% of their genome, we're looking at base pairs, but when we say that modern Eurasians have 1-4% of their genome from Neanderthals we're looking at genes.
- Camillo 10y agoThanks, that makes sense.
- snovv_crash 10y agoBecause we were already 99.x percent the same as Neanderthal, so if you take 4% of a Neanderthal genome and replace those sections in a human genome, not very much actually changes.
- hwillis 10y agoOf normal human genetic variation, 1-4% is sourced from Neanderthal DNA, which sub-Saharan African peoples do not share. They still may share up to 96-99% DNA variations. In absolute terms they share in excess of 99.9%[1]. The variations inside ethnic groups are almost 16 times larger than the variations between ethnic groups. [1]: http://www.telegraph.co.uk/news/worldnews/northamerica/usa/1416706/DNA-survey-finds-all-humans-are-99.9pc-the-same.html http://www.telegraph.co.uk/news/worldnews/northamerica/usa/1...