5 ms·

Scar-free wound healing could be on its way

53 points by awqrre 10y ago

gumby 10y ago
Rats, I was hoping this was a more general "fix" so that there would not be scarring on internal organs after surgery or other trauma. No word on flexibility if the resulting tissue. Scars tend to be quite keratinicious and stiff. Still, an esthetic improvement is better than nothing, especially in facial injuries like the example picture.
- phkahler 10y ago
  Iodine does wonders for healing scars, both during and after formation.
  - slv77 10y ago
    Interesting, same mechanism https://www.ncbi.nlm.nih.gov/m/pubmed/19168293/ https://www.ncbi.nlm.nih.gov/m/pubmed/19168293/ >Topical iodine induces hair growth in and around scars. Hair is regeneration's workhorse, moving purposefully in all directions
    - phkahler 10y ago
      OK, now I'm giving more thought to putting Iodine on my scalp to see if I regrow some of that thinning hair...
dzhiurgis 10y ago
Interesting thing I've heard in Regeneritive Medicine podcast - burn victim skin stem cells are just too good at their job and render too much skin. Hence someone found process how to slow it and result in better looking skin.
reasonattlm 10y ago
Original publicity materials: https://www.pennmedicine.org/news/news-releases/2017/january/using-fat-to-help-wounds-heal-without-scars https://www.pennmedicine.org/news/news-releases/2017/january... Paper: https://dx.doi.org/10.1126/science.aai8792 https://dx.doi.org/10.1126/science.aai8792 This is somewhat different from earlier lines of research into scarless healing in mammals, such as the work based on the biochemistry of MRL mice ( https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3806350/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3806350/ ).
tyingq 10y ago
Interesting point that they can already induce hair follicles to form. That would be newsworthy on its own, wouldn't it? (assuming it would work on male pattern baldness)
bayouborne 10y ago
Not as long as Renee Tucker of College Park, Georgia is still breaking hearts. It's 30 years gone and I can feel it as if it were yesterday..

53 points by awqrre 10y ago

gumby 10y ago

Rats, I was hoping this was a more general "fix" so that there would not be scarring on internal organs after surgery or other trauma. No word on flexibility if the resulting tissue. Scars tend to be quite keratinicious and stiff. Still, an esthetic improvement is better than nothing, especially in facial injuries like the example picture.

phkahler 10y ago
Iodine does wonders for healing scars, both during and after formation.
- slv77 10y ago
  Interesting, same mechanism https://www.ncbi.nlm.nih.gov/m/pubmed/19168293/ https://www.ncbi.nlm.nih.gov/m/pubmed/19168293/ >Topical iodine induces hair growth in and around scars. Hair is regeneration's workhorse, moving purposefully in all directions
  - phkahler 10y ago
    OK, now I'm giving more thought to putting Iodine on my scalp to see if I regrow some of that thinning hair...

dzhiurgis 10y ago

Interesting thing I've heard in Regeneritive Medicine podcast - burn victim skin stem cells are just too good at their job and render too much skin. Hence someone found process how to slow it and result in better looking skin.

reasonattlm 10y ago

Original publicity materials: https://www.pennmedicine.org/news/news-releases/2017/january/using-fat-to-help-wounds-heal-without-scars https://www.pennmedicine.org/news/news-releases/2017/january... Paper: https://dx.doi.org/10.1126/science.aai8792 https://dx.doi.org/10.1126/science.aai8792 This is somewhat different from earlier lines of research into scarless healing in mammals, such as the work based on the biochemistry of MRL mice ( https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3806350/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3806350/ ).

tyingq 10y ago

Interesting point that they can already induce hair follicles to form. That would be newsworthy on its own, wouldn't it? (assuming it would work on male pattern baldness)

bayouborne 10y ago

Not as long as Renee Tucker of College Park, Georgia is still breaking hearts. It's 30 years gone and I can feel it as if it were yesterday..