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Its interesting that obesity map is indistinguishable from a map of type-II diabetes. A reasonable hypothesis, given a virus that sucks glucose out of the bloo
by VLM 10y ago
Its interesting that obesity map is indistinguishable from a map of type-II diabetes.
A reasonable hypothesis, given a virus that sucks glucose out of the blood and fills tissue with fat, is that the higher blood glucose levels of type 2 diabetes would supercharge fat production in those infected with the virus.
So if the patient is infected, and their blood sugar goes up 20%, their fat production will go up 20% regardless of diet. I can see how that would quickly result in very fat diabetes patients.
It would be fascinating to separate the disease symptoms of type-2 diabetes that are caused solely by obesity from those caused solely by blood sugar.
Obviously it would be easier to recover from type-2 diabetes related obesity if a viral infection that essentially creates fat were not turbocharged because of blood chemistry reasons at the same time as the patient is trying to lose fat.
Another interesting study would be children. Anecdotally they can eat hundreds of pounds of sugar and dozens of gallons of corn syrup and remain skinny, until suddenly, perhaps after infection, or perhaps after their pancreas gives out causing a blood sugar rise, they explode in fatness given the same or even lower carb intake.
Quite possibly due to the infection, high blood sugar is causing fatness rather than the other way around, with some interesting implications for treatment. Normally artificially lowering blood sugar would seem to shove it into the fat generation path, but if high blood sugar is turbo charging the infection, perhaps lower blood sugar levels would paradoxically cause weight loss...
You could also run a study of low carb diet success and failure vs infection rate. People with low level semi-diagnosed type-2 diabetes (its a spectrum not a binary) should respond extremely well to a low carb weight loss diet... uninfected people or people infected but without type-2 symptoms should not respond very well to a low carb weight loss diet.