When the men were regularly active and ran, this lead to a healthful reduction of triglycerides. But when the men instead sat for 14 hours a day, running d

When the men were regularly active and ran, this lead to a healthful reduction of triglycerides. But when the men instead sat for 14 hours a day, running did not bring down the high levels of triglycerides in their blood. Sitting seems to have made the men’s bodies exercise-resistant. Inactivity altered the men’s physiology in ways that apparently prevented exercise from improving the metabolism of fat.