True this. But * Learning CSS is not the first priority of a bootstrapped business. The cost associated with a 100kb of css is much lesser compared to creatin

True this. But * Learning CSS is not the first priority of a bootstrapped business. The cost associated with a 100kb of css is much lesser compared to creating a layout and all other styles. * Learning CSS to create a whole layout from scratch can be a daunting task for the uninitiated. * The best approach would be to start the project with Bootstrap, create a winning product, and iterate to find the best layout you need. Then in a subsequent release, you can redo the same using css. CSS Flex is very easy once you get the hang of it and you do not need any other css layout framework.