> [endocannabinoids] - Endocannabinoid_system#Role_in_hippocampal_neurogenesis https://en.wikipedia.org/wiki/Endocannabinoid_system#Role_in_hippocampal_neuroge

> [endocannabinoids] - Endocannabinoid_system#Role_in_hippocampal_neurogenesis https://en.wikipedia.org/wiki/Endocannabinoid_system#Role_in_hippocampal_neurogenesis https://en.wikipedia.org/wiki/Endocannabinoid_system#Role_in... >> In the adult brain, the endocannabinoid system facilitates the neurogenesis of hippocampal granule cells.[37][38] In the subgranular zone of the dentate gyrus, multipotent neural progenitors (NP) give rise to daughter cells that, over the course of several weeks, mature into granule cells whose axons project to and synapse onto dendrites on the CA3 region.[39] NPs in the hippocampus have been shown to possess fatty acid amide hydrolase (FAAH) and express CB1 and utilize 2-AG.[38] Intriguingly, CB1 activation by endogenous or exogenous cannabinoids promote NP proliferation and differentiation; this activation is absent in CB1 knockouts and abolished in the presence of antagonist.[37][38] - "Cannabinoids promote embryonic and adult hippocampus neurogenesis and produce anxiolytic- and antidepressant-like effects" https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1253627/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1253627/ - https://en.wikipedia.org/wiki/Hippocampus https://en.wikipedia.org/wiki/Hippocampus - https://en.wikipedia.org/wiki/Neurogenesis https://en.wikipedia.org/wiki/Neurogenesis