Of course you have to understand HTML/CSS very well to do good. But it's not going to be efficient to start from that. Luckily Photoshop has a working javascrip

Of course you have to understand HTML/CSS very well to do good. But it's not going to be efficient to start from that. Luckily Photoshop has a working javascript engine and it's relatively easy to completely automate HTML/CSS/sprites generation and iterate very quickly. Or even better, switch to Inkscape and generate everything from an SVG XML file. We are moving towards all SVGs websites anyway.