3 ms·

They simulate neurogenesis, I guess, but they do not incorporate the most interesting part of that neurogenesis: That is the new neurons are born into the dent

They simulate neurogenesis, I guess, but they do not incorporate the most interesting part of that neurogenesis: That is the new neurons are born into the dentate gyrus, a region thought to have a particular capacity to orthoganalize feature representations that are similar (e.g. pattern separate) allowing distinct memories to be formed for similar events. The dentate gyrus outputs to a region called Cornu ammonis 3 (CA3) which is heavily recurrent, and thought to br able to pattern complete a full representation from partial inputs. That is, CA3 can encode and retrieve the relations between 2 or more features or objects. For a mathematical model and review one might read: Rolls (2013) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3812781/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3812781/ but many others exist. I'd write more but typing in my phone is driving me to distraction.

arkymark 10y ago
this is really interesting, where/how did you learn this? I'd like to learn more about these things - brain regions, connections, functions - and what they might imply about the kinds of computations that are going on, but my background is mainly on the AI/math side of things.
- SubiculumCode 10y ago
  My dissertational research was on the development of the subfields of the hippocampus in childhood. So these papers from the rat literature were relevant and often inspiring.
- SubiculumCode 10y ago
  I'd like to add that our knowledge of the details of hippocampal neuroanatomy are probably the most advanced of any brain region, which allows the somewhat informed construction of computational models. I wish I had more time to learn modeling methods, I have specific developmental hypotheses I'd like to test in such a model. In the end, I'd probably need to find a knowledgable collaborator though.
- infinite8s 10y ago
  One place to start is the "Principles of Neural Science", the intro textbook to neuroscience.

arkymark 10y ago

this is really interesting, where/how did you learn this? I'd like to learn more about these things - brain regions, connections, functions - and what they might imply about the kinds of computations that are going on, but my background is mainly on the AI/math side of things.

SubiculumCode 10y ago
My dissertational research was on the development of the subfields of the hippocampus in childhood. So these papers from the rat literature were relevant and often inspiring.
SubiculumCode 10y ago
I'd like to add that our knowledge of the details of hippocampal neuroanatomy are probably the most advanced of any brain region, which allows the somewhat informed construction of computational models. I wish I had more time to learn modeling methods, I have specific developmental hypotheses I'd like to test in such a model. In the end, I'd probably need to find a knowledgable collaborator though.
infinite8s 10y ago
One place to start is the "Principles of Neural Science", the intro textbook to neuroscience.