I just tested moving my Typescript/React template to Google Closure using a webpack plugin. It came in at 148KB with UglifyJS, and 102KB with Google Closure run

I just tested moving my Typescript/React template to Google Closure using a webpack plugin. It came in at 148KB with UglifyJS, and 102KB with Google Closure running after Typescript did the ES5 conversion. This may not be the "integration" some are seeking but it's sure a step ahead.