3 ms·
It's essential to the growth pattern of dendrites that neurons are able to recognize and avoid themselves. There's evidence that alternative splicing (the genet
by spqr0a1 10y ago
It's essential to the growth pattern of dendrites that neurons are able to recognize and avoid themselves. There's evidence that alternative splicing (the genetic differences you mentioned) arose in cadherins before even the immune system. Basically alternative splicing provides each neuron with a random key that has a ~1/30,000 chance of collision.
- Symmetry 10y agoThis gets encoded into some sort of external marker I assume?
- spqr0a1 10y agoYup, cadherins are transmembrane proteins and the variable domains are exposed on the external surface.
- berdon 10y agoOut of curiosity - do you have any suggested reading to learn more about the brain at this depth?