Actually there's more evidence for that happening in the lower intestine which can "taste" sweet things. Recent studies have shown that this receptor is also e

Actually there's more evidence for that happening in the lower intestine which can "taste" sweet things. Recent studies have shown that this receptor is also expressed in the extragustatory system, including the gastrointestinal tract, pancreatic β-cells, and glucose-responsive neurons in the brain. In the intestine, the sweet taste receptor regulates secretion of incretin hormones and glucose uptake from the lumen. In β-cells, activation of the sweet taste receptor leads to stimulation of insulin secretion. Collectively, the sweet taste receptor plays an important role in recognition and metabolism of energy sources in the body. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3221019/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3221019/ Also check out https://www.scientificamerican.com/article/your-intestines-can-taste-sugar/ https://www.scientificamerican.com/article/your-intestines-c... Sidebar: I know calories in / calories out vs diets that restrict food groups (e.g. Carbs) is a holy war but there's a whole wealth of info now that supports avoiding foods that cause an insulin response (which starts up fat storage mode). That might not be healthy for everyone but I've experienced first hand how effective it can be.