What is your goal, investment or bootstrapping? If you're trying to make a POC as fast as possible to get investment, use whichever language you are fastest in

What is your goal, investment or bootstrapping? If you're trying to make a POC as fast as possible to get investment, use whichever language you are fastest in, even if it's not perfect. Be OK with the idea of throwing it away when you write a better V2 after investment. If you're planning to bootstrap and need to rely on stability with a very small team for a long time, choose whichever lang you know best how to make repeatable success, even if it takes longer. There's also no reason everything has to be written in the same lang. I'm NOT saying go full tiny microservices, but use what is efficient where it makes sense. E.g. I run a TLS terminator in C (bud), it's one binary and one config file. My service discovery is Golang (consul), again one binary one config. Think Unix philosophy, one tool for one job. And if you're using an automatic services router like Fabio, Envoy, or Traefik, it's super easy to connect these services regardless of lang. (There really is no equivalent for these in Node, especially not up to my production standards.) This pattern has served me well across three startups (inc. medium SaaS) and countless projects. I'm primarily Node but I would definitely recommend using .NET where you see it providing a clear solution for one of your concerns.