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Agree. Let me add. Infantile/childhood amnesia has many causes, but being unable to form a memory is not one of them. Memories in infancy are fragile, and conte
by SubiculumCode 10y ago
Agree. Let me add. Infantile/childhood amnesia has many causes, but being unable to form a memory is not one of them. Memories in infancy are fragile, and context dependent, and even if retained through life are likely fragmentary, non-verbal, non-conceptually embedded, that we'd not recognize it as an episodic memory. Moreover, the medial temporal lobes and hippocampus (brain region critical to relational memory formation) are still immature before age 2, before which time the dentate gyrus in the tri-synaptic circuit of the hippocampus may not be fully operational, potentially leading to massive interference between similar memories from less efficient representational separation and a bias towards pattern completion. The last tidbit is particularly interesting as such a bias to pattern completion may support the rapid semantic knowledge acquisitions occurring early in life, which may benefit from layering of similar representations to extract reoccurring key features about the world, as opposed to the more efficient pattern separation later in life that allows more fine grained memory distinctions to be retained and allowing individual events to be better remembered.