With the rise of terrestrial plants and animals approximately 400 Myr ago, the major functions of CYPs expanded to encompass the detoxification of dietary phyto

With the rise of terrestrial plants and animals approximately 400 Myr ago, the major functions of CYPs expanded to encompass the detoxification of dietary phytochemicals via a coevolutionary process involving dozens of gene duplication events (Nelson 1999; Lewis 2001). There are approximately 76 CYP families known in animals, with 57 of these present in humans (Nelson et al. 2004). http://rspb.royalsocietypublishing.org/content/275/1640/1231.figures-only http://rspb.royalsocietypublishing.org/content/275/1640/1231...