The only thing that's hit me (so far as I know) in years was an Acrobat Reader 0day that my installed antivirus missed (AVG? I think? years ago) but once I figu

The only thing that's hit me (so far as I know) in years was an Acrobat Reader 0day that my installed antivirus missed (AVG? I think? years ago) but once I figured out how to sigkill the payload while it was still starting up, Hitman Pro ate it alive in short order. Windows Defender is apparently pretty good but it's never found anything to complain about on my systems except copies of EICAR in a local CPAN mirror. So, for me, as far as I can tell, "don't use IE" plus "don't install random crap you downloaded from the internet" plus "my mail client is mutt under screen on a server" between them are basically sufficient defense these days. How far that generalises I can't really say.