Aside from cost, is there any reasonable technical reason to not have 32/64GB options available? My desktop in 2000 had 2GB of ram, and I'm shocked that 16 year

Aside from cost, is there any reasonable technical reason to not have 32/64GB options available? My desktop in 2000 had 2GB of ram, and I'm shocked that 16 years later my laptop maxes at 16GB. I remember in 2009 building a server with 32GB and the memory was only a few hundred for decent ECC RAM.