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I just finished a book by Nick Lane where he discussed how he believes aging is cause by mitochondrial free-radical leakage. His hypothesis (and he is a smart g

I just finished a book by Nick Lane where he discussed how he believes aging is cause by mitochondrial free-radical leakage. His hypothesis (and he is a smart guy) is that science will allow people to live longer, but probably not much longer than 125. https://www.ncbi.nlm.nih.gov/pubmed/20021368 https://www.ncbi.nlm.nih.gov/pubmed/20021368

neom 10y ago
What's the book? Would like to read it. Thanks.
- JohnDotAwesome 10y ago
  The Vital Question. As a layman -- and an audio book listener -- this wasn't an easy book to get through! Still, it caused me to sit and think a little, and that was the whole point.
  - neom 10y ago
    Thank you. (audiobook listener also)
- misiti3780 10y ago
  it is talked about a bit in The Vital Question [1] and a more in depth in Power, Sex, and Suicide [2] His books are honestly life changing, i can recommend them or him enough. [1] https://www.amazon.com/Vital-Question-Evolution-Origins-Complex/dp/0393352978/ref=asap_bc?ie=UTF8 https://www.amazon.com/Vital-Question-Evolution-Origins-Comp... [2] https://www.amazon.com/Power-Sex-Suicide-Mitochondria-Meaning/dp/0199205647/ref=asap_bc?ie=UTF8 https://www.amazon.com/Power-Sex-Suicide-Mitochondria-Meanin...
  - neom 10y ago
    Thank you.
trhway 10y ago
>but probably not much longer than 125. enter new organs growth. Any organ, except for the brain, could be replaced by a new one, and thus there is no limit. Brain probably too can be updated in some ways, we just don't know how yet.
- misiti3780 10y ago
  im not a biologist (anyone qualified to comment please do) but i dont think the new organs will stop the free-radical leakage. it occurs in every cell in your body, organs are only a small portion of those cells.
- drcross 10y ago
  As a layman it seems far easier to repair existing damage using nanomachine than to replace organs.
  - TeMPOraL 10y ago
    Not really. We have organ-growing capability, we don't have organ repair capability. It's easier to repurpose the former than invent the latter.
rsync 10y ago
I highly recommend the book - Power, Sex, Suicide - that the parent is referring to. Nick Lanes other long form book, Oxygen, is also very, very good.
Evgeny 10y ago
His hypothesis (and he is a smart guy) is that science will allow people to live longer, but probably not much longer than 125. Not exactly! I just finished the same book and the exact quote is: I doubt we will ever find a way of living much beyond 120 by merely fine-tuning our physiology. So he's a smart guy indeed! He says that there still may be ways to extend lifespan, but they have to be more radical compared to just fine-tuning physiology.

neom 10y ago

What's the book? Would like to read it. Thanks.

JohnDotAwesome 10y ago
The Vital Question. As a layman -- and an audio book listener -- this wasn't an easy book to get through! Still, it caused me to sit and think a little, and that was the whole point.
- neom 10y ago
  Thank you. (audiobook listener also)
misiti3780 10y ago
it is talked about a bit in The Vital Question [1] and a more in depth in Power, Sex, and Suicide [2] His books are honestly life changing, i can recommend them or him enough. [1] https://www.amazon.com/Vital-Question-Evolution-Origins-Complex/dp/0393352978/ref=asap_bc?ie=UTF8 https://www.amazon.com/Vital-Question-Evolution-Origins-Comp... [2] https://www.amazon.com/Power-Sex-Suicide-Mitochondria-Meaning/dp/0199205647/ref=asap_bc?ie=UTF8 https://www.amazon.com/Power-Sex-Suicide-Mitochondria-Meanin...
- neom 10y ago
  Thank you.

trhway 10y ago

>but probably not much longer than 125. enter new organs growth. Any organ, except for the brain, could be replaced by a new one, and thus there is no limit. Brain probably too can be updated in some ways, we just don't know how yet.

misiti3780 10y ago
im not a biologist (anyone qualified to comment please do) but i dont think the new organs will stop the free-radical leakage. it occurs in every cell in your body, organs are only a small portion of those cells.
drcross 10y ago
As a layman it seems far easier to repair existing damage using nanomachine than to replace organs.
- TeMPOraL 10y ago
  Not really. We have organ-growing capability, we don't have organ repair capability. It's easier to repurpose the former than invent the latter.

rsync 10y ago

I highly recommend the book - Power, Sex, Suicide - that the parent is referring to. Nick Lanes other long form book, Oxygen, is also very, very good.

Evgeny 10y ago

His hypothesis (and he is a smart guy) is that science will allow people to live longer, but probably not much longer than 125. Not exactly! I just finished the same book and the exact quote is: I doubt we will ever find a way of living much beyond 120 by merely fine-tuning our physiology. So he's a smart guy indeed! He says that there still may be ways to extend lifespan, but they have to be more radical compared to just fine-tuning physiology.