No doubt there are confounding factors to the influence of ADT, such as surgery, radiation, or other support meds. But the impact of long term exposure to canc

No doubt there are confounding factors to the influence of ADT, such as surgery, radiation, or other support meds. But the impact of long term exposure to cancer cells can't be discounted either. Because slow growing cancer is a fairly recent phenomenon, I suspect living with active cancer for 5-10 years is probably not well documented or fully quantified yet. The effects of such stress on the immune system alone must lead to uncharted waters. There's other evidence that persistent inflammation (or protein glycosylation?) may accelerate dementia, as suggested by the ~45% protective effect of Actos (pioglitazone) against dementia, for both those with and without diabetes. http://www.nytimes.com/2006/07/17/health/17alzheimer.html?_r=0 http://www.nytimes.com/2006/07/17/health/17alzheimer.html?_r...