Being in the middle of a struggle with Javascript tooling (Javascript, ES5 v/s ES6, typescript, webpack v/s System.js, shims, pollyfils, npm downloading the int

Being in the middle of a struggle with Javascript tooling (Javascript, ES5 v/s ES6, typescript, webpack v/s System.js, shims, pollyfils, npm downloading the internet, etc, etc) I can't but imagine that there should be a better way. How much I would like Webassembly to be ready to open the gates to other languages on the frontend land. Anyone here has more information about webassembly / python on the browser? I would love to know what is the current state of the art of running python on the browser and contribute to make the dream come true. I have on my radar Brython [0], py.js [1](seems to be abandoned) and pypy.js [2] [0] http://www.brython.info/ http://www.brython.info/ [1] http://pyjs.org/ http://pyjs.org/ [2] http://pypyjs.org/ http://pypyjs.org/