Usually React, using this boilerplate: https://github.com/davezuko/react-redux-starter-kit https://github.com/davezuko/react-redux-starter-kit which has Webpack

Usually React, using this boilerplate: https://github.com/davezuko/react-redux-starter-kit https://github.com/davezuko/react-redux-starter-kit which has Webpack and testing already set up. For APIs I either use Express if it's really small, or Django/Django Rest Framework/Postgres if I want something with admin pages.