I recommend buying a vertical mouse if you're doing a lot of precision mouse work. I generally don't consider surfing the web precision work, and I can offload

I recommend buying a vertical mouse if you're doing a lot of precision mouse work. I generally don't consider surfing the web precision work, and I can offload a lot of muscle twitching to the scroll button. You can use ambient lighting which changes color to match what's on the screen. This is a well known technique to reduce eye strain. Grab yourself a decent chair with memory foam padding. A lot of the pain that comes from sitting is in the lower back, so it's absolutely crucial that the lower back is looked after. A lot of the other comments regarding breaks and eye strain are generally fine, but can be overdone very easily. Flux + eyeglasses + antiglare screen covers combined together can be overkill. Try to use autofill as much as possible and isolate applications so everything is not in one place and thus difficult to find. For example, I have one browser for Reddit, one browser for hackernews, one browser for casual surfing, etc. I'm pretty sure an SSD can handle multiple contextual browser like this and it doesn't take long to split a browser up like this, and believe me it's worth it!