11 ms·

recent update: http://www.nationalmssociety.org/news/news-detail/index.aspx?nid=2206 http://www.nationalmssociety.org/news/news-detail/index.aspx... "On Februa

by davi 17y ago

recent update: http://www.nationalmssociety.org/news/news-detail/index.aspx?nid=2206 http://www.nationalmssociety.org/news/news-detail/index.aspx... "On February 10, 2010, the University at Buffalo Medical Center released a press release describing preliminary results from an ongoing study led by Dr. Robert Zivadinov combining the use of transcranial and extracranial venous doppler evaluation in people with MS and controls, with the aim of evaluating the prevalence of venous obstruction in people with MS. [...] The results reported are based on the first 500 participants in the Combined Transcranial and Extracranial Venus Doppler Evaluation study. The preliminary results reported that at least 55 percent of the MS cohort participating in the initial phase of the study showed narrowing of the extracranial veins causing restriction of normal outflow of blood from the brain. This was also true for at least 22 percent of the healthy controls." So it looks like the MS research community has significant interest in this, and that early reports from a larger study confirm an association between the disease and venous blockage. --- edit: and on the other hand... http://medicalmyths.wordpress.com/2009/11/24/the-zamboni-myth-ccsvi-surreal/ http://medicalmyths.wordpress.com/2009/11/24/the-zamboni-myt...

warfangle 17y ago
That medicalmyths blog also rails against coronary bypass surgery. I tried to find out who this Colin Rose is (as he lists no credentials whatsoever anywhere on the blog), and the only Colin Rose I found was a statistician with no medical training. (He also says MS symptoms are susceptible to the placebo effect; while this may be true, I doubt they could be cured by said placebo effect) The entire blog seems even fishier than the trials Zamboni performed.
- davi 17y ago
  Yeah that blog smells pretty ripe to me, too. I don't trust invective. But it's worth knowing it's there if one is going to dig into this topic a bit further.
- rsheridan6 17y ago
  It says in the about page >Colin Rose MD PhD, Cardiologist, Associate Professor of Medicine, McGill University And there are questions about whether CABG really reduces mortality or not. As for Zamboni's procedure, I was psyched about it until I read Rose's debunking, and then some posts in a forum for MS patients by someone who had the surgery and is still having problems with MS. I'm not going to say for sure that it's BS, but I'm skeptical.
  - niels_olson 17y ago
    As a doc, the more I read of Colin Rose's blog, the more I agree him. The more I read about Zamboni, the less I agree with him.
  - jonny_noog 17y ago
    I read the original article from The Globe and Mail with much interest the first time it appeared on HN. I have now also read Colin Rose's assessment. Obviously it's pretty early days and I am all for being cautious and skeptical. I don't wish to submit a person I care about to an unproven procedure whose possible risks I know very little of. But to brand Zamboni as some kind of backwards witch doctor and call for no further investigation to even take place into this possible avenue of treatment seems beyond the pale to me. Surely this attitude must come from people who have not been personally affected by MS and/or have not had to watch someone they care about suffer from its bizarre, seemingly random and quality of life destroying symptoms. I would be very interested in any further links you could provide in relation to the Zamboni treatment (e.g. you mention a discussion on a forum) either for or against.
  - warfangle 17y ago
    Huh - his about page must have changed - or been fixed. All that was there when I looked was a listing of essays.

by davi 17y ago

warfangle 17y ago

That medicalmyths blog also rails against coronary bypass surgery. I tried to find out who this Colin Rose is (as he lists no credentials whatsoever anywhere on the blog), and the only Colin Rose I found was a statistician with no medical training. (He also says MS symptoms are susceptible to the placebo effect; while this may be true, I doubt they could be cured by said placebo effect) The entire blog seems even fishier than the trials Zamboni performed.

davi 17y ago
Yeah that blog smells pretty ripe to me, too. I don't trust invective. But it's worth knowing it's there if one is going to dig into this topic a bit further.
rsheridan6 17y ago
It says in the about page >Colin Rose MD PhD, Cardiologist, Associate Professor of Medicine, McGill University And there are questions about whether CABG really reduces mortality or not. As for Zamboni's procedure, I was psyched about it until I read Rose's debunking, and then some posts in a forum for MS patients by someone who had the surgery and is still having problems with MS. I'm not going to say for sure that it's BS, but I'm skeptical.
- niels_olson 17y ago
  As a doc, the more I read of Colin Rose's blog, the more I agree him. The more I read about Zamboni, the less I agree with him.
- jonny_noog 17y ago
  I read the original article from The Globe and Mail with much interest the first time it appeared on HN. I have now also read Colin Rose's assessment. Obviously it's pretty early days and I am all for being cautious and skeptical. I don't wish to submit a person I care about to an unproven procedure whose possible risks I know very little of. But to brand Zamboni as some kind of backwards witch doctor and call for no further investigation to even take place into this possible avenue of treatment seems beyond the pale to me. Surely this attitude must come from people who have not been personally affected by MS and/or have not had to watch someone they care about suffer from its bizarre, seemingly random and quality of life destroying symptoms. I would be very interested in any further links you could provide in relation to the Zamboni treatment (e.g. you mention a discussion on a forum) either for or against.
- warfangle 17y ago
  Huh - his about page must have changed - or been fixed. All that was there when I looked was a listing of essays.