> won't bacteria lose their resistance after a while? DNA is good at accumulating, and relatively poor at editing out. Some bacteria will lose resistance, just

> won't bacteria lose their resistance after a while? DNA is good at accumulating, and relatively poor at editing out. Some bacteria will lose resistance, just like your ancestors lost the ability to make Vitamin C. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3145266/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3145266/ but you only need one single bacteria to have not lost the ability. > What if we cycle certain antibiotics on an annual basis? it helps. We can also stack them, and use multiple attacks at the same time. which also helps. But it just delays the inevitable. > When we reintroduce them, they'll be more powerful. Right? the bacteria, yes. because they'll have accumulated defense mechanisms. Ultimately, I think we win this race, because we can intelligently and actively edit DNA.