3 ms·
FWIW, LD50 dosage is low for intravenous injection, but very high (multiple orders of magnitude higher) for intramuscular injection. The risk is generally not g
by HillRat 10y ago
FWIW, LD50 dosage is low for intravenous injection, but very high (multiple orders of magnitude higher) for intramuscular injection. The risk is generally not getting enough of a dosage, not too little, unless you somehow manage to hit a vein.
The main problem is that, if you're carrying around EpiPens for allergic anaphylaxis, particularly for a child, dealing with syringes and bottles isn't really a practical solution for day-to-day living (and definitely not an option if you're carrying them around for yourself -- hard to carry out delicate medical procedures while being unable to breathe). There are probably a lot of people without access to autoinjectors who have had to suffer the consequences of anaphylactic shock.
- contingencies 10y ago"The LD50 value for adrenaline in control animals was 11.1 mg/kg b.wt" http://www.ncbi.nlm.nih.gov/pubmed/6087619 http://www.ncbi.nlm.nih.gov/pubmed/6087619 That means for an average human, LD50 = ~10 x 70 = 700mg... or perhaps more for typically overweight Americans. Conclusion: Scare factor is being used to justify the market... you have been had.